To make your humor work, you should ______.

参考解析：

细节理解题。根据文章第一段前三句“If you intend using humor in your talk to make people smile, you must know how to identify shared experiences and problems. Your humor must be relevant to the audience and should help to show them that you are one of them or that you understand their situation and are in sympathy with their point of view. Depending on whom you are addressing, the problems will be different”可知，如果你打算在谈话中使用幽默来使人们微笑，你必须知道如何识别共同的经历和问题。你的幽默必须与听众相关，应该有助于向他们表明，你是他们中的一员，或者你了解他们的处境，并且赞同他们的观点。取决于你在和谁说话，问题会有所不同。故选C。